Dr. Sameer Awadhiya MBBS , Pediatrics

D Bose MP helps in weight loss by reducing appetite and food intake. It also increases the insulin sensitivity in your body to work more effectively. This lead to decreased glucose production increases the use of glucose and decrease the fat deposition further helps in weight loss. However, D Bose MP is not approved for weight loss, this is an off-label use.

ravi udawat MBBS , General Physician

D Bose MP should be taken with food to reduce stomach and bowel side effects, which may experience the first few weeks of treatment. Also, exercise regularly and test for sugar in your blood or urine as directed.

Dr. Bharat MBBS , General Physician

The long-term use can lead to the deficiency of Vitamin B12, which can further lead to megaloblastic anemia. Furthermore, Long-term Metformin use can also lead to kidney and liver problems. 

Dr. Vipin Khadse MBBS , General Physician

D Bose MP is not a known cause of alopecia (hair loss). However, the conditions treated by D Bose MP type 2 diabetes and PCOS, often list hair loss as a possible symptom.

Dr. Manoj Meena MBBS , General Physician

Lactic acidosis associated with D Bose MP treatment is a rare but fatal adverse effect. Lactic acidosis appears to result from biguanide interference causing an increase in production and decrease in clearance of lactate leading to higher cellular lactate levels. A decrease in pyruvate carboxylase activity, the rate-limiting enzyme in the formation of glucose from lactate, can also decrease hepatic metabolism of lactate. leading to increasing lactic acidosis. Signs and symptoms of D Bose MP induced lactic acidosis are nonspecific and include anorexia, nausea, vomiting, altered level of consciousness, hyperpnoea, abdominal pain, and thirst.