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Chloral is a prescription medicine that is available as a Capsule, Drops. Primarily, it is used for the treatment of Bacterial Infections. Secondary and off-label uses of Chloral have also been mentioned below.
The optimal dosage of Chloral is largely dependent on the individual's body weight, medical history, gender and age. Besides the medical condition it is advised for, the route of administration also plays an important role in determining the correct drug dosage. Detailed information has been provided in the dosage section.
Some other side effects of Chloral have been listed ahead. These side effects of Chloral are usually temporary and subside with the completion of treatment. If, however, they worsen or do not go away, please speak with your physician.
Chloral's effect during pregnancy is Severe and Severe while nursing. In addition, Chloral's effects on the liver, heart and kidney are discussed below in the Chloral related warnings section.
Chloral is contraindicated in people with pre-existing medical conditions like Kidney Disease, Liver Disease as it can result in adverse effects. Some other conditions that can be affected by Chloral are listed in the contraindications section below.
Besides this, Chloral may also have severe interaction with some medicines. A complete list of these interactions is given below.
In addition to these precautions, you may also note that Chloral is safe while driving, and is is addictive in nature.
Chloral is used to treat the following -
Main Benefits
Other Benefits
This is the usual dosage recommended in most common treatment cases. Please remember that every patient and their case is different, so the dosage can be different based on the disease, route of administration, patient's age and medical history.
Find the right dosage based on disease and age
Age Group | Dosage |
Is the use of Chloral safe for pregnant women?
Pregnant women may get severe side effects after taking Chloral. If you are pregnant, do not take Chloral without a doctor's advice.
Is the use of Chloral safe during breastfeeding?
Women who are breastfeeding may experience severe harmful effects after taking Chloral. It should only be taken after medical advice.
What is the effect of Chloral on the Kidneys?
Chloral has very mild side effects on the kidneys.
What is the effect of Chloral on the Liver?
Chloral can have moderate side effects on the liver. If you notice any harmful effects then stop taking this drug right away. Consult your doctor before using this medicine again.
What is the effect of Chloral on the Heart?
There may be an adverse effect on the heart after taking Chloral. If you observe any side effects on your body then stop taking this drug. Restart this medicine only if your doctor advises you to do so.
Chloral should not be taken with following medicines due to severe side effects it may cause to patients -
Moderate
If you are suffering from any of the following diseases, you should not take Chloral unless your doctor advises you to do so -
Is this Chloral habit forming or addictive?
No, you will not get addicted to Chloral.
Is it safe to drive or operate heavy machinery when consuming?
Yes, it is safe to do these activities or work after taking Chloral as it does not make you drowsy.
Is it safe?
Yes, but consume Chloral only on doctor's advice.
Is it able to treat mental disorders?
Chloral is unable to treat or cure mental disorders.
Interaction between Food and Chloral
Chloral may take longer to act if you eat some foods while taking it. Follow your doctor's advice on this.
Interaction between Alcohol and Chloral
It is difficult to say anything about the effect of Chloral and alcohol. No research has been done on this yet.
Yes, Chloral can be taken with ibuprofen. No harmful drug interaction has been reported between them. However, if you feel any discomfort after taking this drug do not hesitate to inform your doctor.
Chloral contains chloramphenicol which is a broad-spectrum antibiotic that is active against both Gram-positive and Gram-negative bacteria. It works by inhibiting the protein synthesis in bacteria which needs to survive. In the absence of protein, the bacterial growth is stunned and slowed. It can also kill the bacteria in higher doses. Chloral is effective against a wide range of both gram negative and gram positive bacteria such as Salmonella species, Rickettsia species, Neisseria meningitidis, Escherichia coli, Haemophilus influenzae, and Staphylococcus pneumoniae.
Yes, Chloral may cause gray baby syndorme in newborn infants especially in premature baby, if this drug is given in higher doses. Gray baby syndrome is a rare side effect that occurs due to accumulation of the chloramphenicol in the newborn infant. The cause of gray baby syndrome is that the newborn baby lacks the some liver enzymes which are necessary to metabolize and removes this drug from the body. The accumulation of the chloramphenicol in the body leads to toxicity which causes development of symptoms such as vomiting, gray color of the skin, blue discolouration of lips and skin. To avoid gray baby syndrome the doses of Chloral must be lowered and adjusted as per the need.
Yes, Chloral can be taken with paracetamol. No drug-drug interaction has been reported between them. Chloral is safe to take along with paracetamol if taken as recommended.
The dosage of Chloral may vary from case to case as it depends on the type of infection and severity of the infection. You are recommended to take this drug as per your doctor's instructions. Chloral should be taken empty stomach because food may affect absorption of this drug. Precautions must be taken in patients with improper liver or kidney function.
This medicine data has been created by -
B.Pharma, Pharmacy
5 Years of Experience
References
US Food and Drug Administration (FDA) [Internet]. Maryland. USA; Package leaflet information for the user; Chloromycetin sodium succinate (chaloramphenicol sodium succinate)
KD Tripathi. [link]. Seventh Edition. New Delhi, India: Jaypee Brothers Medical Publishers; 2013: Page No 739-742