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Amphen is a prescription drug, available for use as Capsule, Ointment, Syrup. Bacterial Infections are some of its major therapeutic uses. Other than this, Amphen has some other therapeutic uses, which have been discussed ahead.
The right dosage of Amphen depends on the age, gender, and medical history of the patient. Individual symptoms and route of administration also determines the right dosage. Detailed information has been provided in the dosage section.
Some other side effects of Amphen have been listed ahead. Usually, these side effects of Amphen go away soon, and do not persist beyond the duration of the treatment. However, if these continue for a longer time, consult your doctor right away.
Furthermore, you should know that effect of Amphen is Severe for pregnant women and Severe for women who are breastfeeding. Further, the section on Amphen related warnings talks about Amphen's effects on the liver, heart and kidney.
Individuals suffering from medical conditions like Kidney Disease, Liver Disease must refrain from the use of Amphen since this can cause severe adverse effects. Some other conditions that can be affected by Amphen are listed in the contraindications section below.
Besides this, Amphen may also have severe interaction with some medicines. See below for a complete list.
You should also be aware that Amphen is safe while driving, and is addiction.
Amphen is used to treat the following -
Main Benefits
Other Benefits
This is the usual dosage recommended in most common treatment cases. Please remember that every patient and their case is different, so the dosage can be different based on the disease, route of administration, patient's age and medical history.
Find the right dosage based on disease and age
Age Group | Dosage |
Adult |
|
Geriatric |
|
13 - 18 years (Adolescent) |
|
2 - 12 years (Child) |
|
Infant (1 month to 2 years) |
|
Based on research, the following side effects have been observed when Amphen is used -
Mild
Is the use of Amphen safe for pregnant women?
Amphen can cause severe side effects if taken during pregnancy, so, pregnant women should talk to their doctor before taking it.
Is the use of Amphen safe during breastfeeding?
Women who are breastfeeding may experience severe harmful effects after taking Amphen. It should only be taken after medical advice.
What is the effect of Amphen on the Kidneys?
Amphen rarely affects the kidneys.
What is the effect of Amphen on the Liver?
You may experience side effects on your liver after taking Amphen. If this happens, then discontinue its use. Consult your medical practitioner, do as he/she suggests.
What is the effect of Amphen on the Heart?
Amphen can have moderate side effects on the heart. If you notice any harmful effects then stop taking this drug right away. Consult your doctor before using this medicine again.
Amphen should not be taken with following medicines due to severe side effects it may cause to patients -
Moderate
If you are suffering from any of the following diseases, you should not take Amphen unless your doctor advises you to do so -
Is this Amphen habit forming or addictive?
No, there is no any evidence that Amphen is addictive.
Is it safe to drive or operate heavy machinery when consuming?
Amphen will not make you feel sleepy or drowsy. So you drive or operate machinery safely.
Is it safe?
Yes, Amphen is safe but you must consult your doctor before taking it.
Is it able to treat mental disorders?
There is no benefit of taking Amphen for mental disorders.
Interaction between Food and Amphen
Taking Amphen with some specific foods may delay its effect. Talk to your doctor about this.
Interaction between Alcohol and Amphen
Information about the interaction of Amphen and alcohol is not currently available because this topic has not been researched yet.
Discontinuing Amphen on your own can increase the chances of bacterial resistance and infection relapse. It is recommended that you always consult your doctor if you have decided to discontinue this medicine.
Amphen contains chloramphenicol which is a broad-spectrum antibiotic that is active against both Gram-positive and Gram-negative bacteria. It works by inhibiting the protein synthesis in bacteria which needs to survive. In the absence of protein, the bacterial growth is stunned and slowed. It can also kill the bacteria in higher doses. Amphen is effective against a wide range of both gram negative and gram positive bacteria such as Salmonella species, Rickettsia species, Neisseria meningitidis, Escherichia coli, Haemophilus influenzae, and Staphylococcus pneumoniae.
Take Amphen as directed by your doctor to ensure complete eradication of infection. Do not take this medicine longer than prescribed to avoid bacterial resistance.
Yes, Amphen may cause gray baby syndorme in newborn infants especially in premature baby, if this drug is given in higher doses. Gray baby syndrome is a rare side effect that occurs due to accumulation of the chloramphenicol in the newborn infant. The cause of gray baby syndrome is that the newborn baby lacks the some liver enzymes which are necessary to metabolize and removes this drug from the body. The accumulation of the chloramphenicol in the body leads to toxicity which causes development of symptoms such as vomiting, gray color of the skin, blue discoloration of lips and skin. To avoid gray baby syndrome the doses of Amphen must be lowered and adjusted as per the need.
Yes, Amphen can be taken with ranitidine. No harmful drug interaction has been reported between them. It is safe to take Amphen along with ranitidine if taken as directed by a doctor. However, if you feel any discomfort after taking this drug do not hesitate to inform your doctor.
This medicine data has been created by -
References
US Food and Drug Administration (FDA) [Internet]. Maryland. USA; Package leaflet information for the user; Chloromycetin sodium succinate (chaloramphenicol sodium succinate)
KD Tripathi. [link]. Seventh Edition. New Delhi, India: Jaypee Brothers Medical Publishers; 2013: Page No 739-742