Adcetris (Brentuximab Vedotin) is an antibody-drug conjugate (ADC) used in the treatment of certain types of cancers, particularly lymphomas. It combines a monoclonal antibody that specifically targets CD30, a protein expressed on the surface of certain cancer cells, with a potent cytotoxic agent. Adcetris offers a targeted therapeutic approach, reducing harm to healthy cells while effectively killing cancer cells.
Adcetris is a groundbreaking therapy offering hope for patients with relapsed or refractory lymphomas. Its targeted mechanism maximizes efficacy while minimizing off-target toxicity. Proper patient selection, monitoring, and adherence to safety protocols are essential for achieving the best outcomes.
Adcetris combines an anti-CD30 monoclonal antibody with monomethyl auristatin E (MMAE), a cytotoxic agent. Once the antibody binds to the CD30 protein on cancer cells, the conjugate is internalized, and MMAE is released, disrupting microtubules and inducing cell death.
Adcetris is used to treat the following -
Other Benefits
This is the usual dosage recommended in most common treatment cases. Please remember that every patient and their case is different, so the dosage can be different based on the disease, route of administration, patient's age and medical history.
Find the right dosage based on disease and age
| Age Group | Dosage |
Based on research, the following side effects have been observed when Adcetris is used -
Severe
Moderate
Common
Is the use of Adcetris safe for pregnant women?
Adcetris can cause severe side effects if taken during pregnancy, so, pregnant women should talk to their doctor before taking it.
Is the use of Adcetris safe during breastfeeding?
Women who are breastfeeding may experience severe harmful effects after taking Adcetris. It should only be taken after medical advice.
What is the effect of Adcetris on the Kidneys?
Adcetris is not harmful for kidneys.
What is the effect of Adcetris on the Liver?
Adcetris is completely safe for the liver.
What is the effect of Adcetris on the Heart?
Adcetris may cause harmful effects on the heart. if you feel it's having any such effect, then stop taking this drug, and restart only on your doctor's advice.
Adcetris should not be taken with following medicines due to severe side effects it may cause to patients -
Severe
Moderate
Mild
If you are suffering from any of the following diseases, you should not take Adcetris unless your doctor advises you to do so -
Is this Adcetris habit forming or addictive?
Adcetris does not cause addiction.
Is it safe to drive or operate heavy machinery when consuming?
No, you should not drive or operate heavy machinery after taking Adcetris as you may feel sleepy.
Is it safe?
Yes, Adcetris is safe but you must consult your doctor before taking it.
Is it able to treat mental disorders?
No, Adcetris is not used to treat mental disorders.
Interaction between Food and Adcetris
There is no information on the effects of taking Adcetris with food, because this topic has not been scientifically researched yet.
Interaction between Alcohol and Adcetris
No research has been done on this till date. Therefore, it is not known what the effect of taking Adcetris with alcohol will be.
This medicine data has been created by -
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