What is Lead Blood test? 

Lead blood test is performed to measure the levels of lead in your blood. 

Lead is a toxic metal that can damage the body organs, especially the brain if inhaled or ingested. It is present in various products including paints, batteries and pesticides. Some traditional remedies and cosmetics also contain lead. 

People who work at mines, construction and auto repair are at high risk of lead toxicity. Additionally, families of these workers may be exposed to lead when some of the lead dust is brought home on work clothes. 

Children are particularly susceptible to lead exposure because they often tend to put their fingers or objects (which may be contaminated with lead) into their mouths. They are also highly vulnerable to lead poisoning than adults because even low levels can hamper their growth and development. 

Although low levels are not considered harmful for adults, continuous exposure to lead or a high dose can be dangerous. In pregnant women, lead exposure may impair foetal neurological development. It may also result in spontaneous abortions or low-birth-weight babies.

  1. How is a Lead Blood test performed?
  2. Why is Lead Blood test performed?
  3. How do you prepare for a Lead Blood test?
  4. Lead Blood test results and normal range

The test requires a small sample of blood which is collected by a finger stick or heel stick (in infants) method. 

The fingerstick method:

  • Any finger on your palm will be cleansed with alcohol and squeezed slightly
  • A sharp needle (lancet) will be used to make a quick puncture
  • A drop of blood will then be collected onto a slide or test strip and sent to the laboratory for testing.

In the heel stick method performed in infants, the sample is collected from the heel in the same way as in the fingerstick method. 

If the initial test shows elevated lead levels in the blood, then a blood sample will be collected from a vein in your arm to confirm the results. 

After the venipuncture, you may notice a slight bruise at the site of blood withdrawal. Though it will subside on its own. If the bruising doesn’t disappear after a few hours, please contact your doctor.

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If you are at risk of environmental exposure to lead, your doctor may order this test for you. The test is also done to monitor the treatment for high lead levels.

As per the local health guidelines, doctors recommend this test for the following at-risk groups:

  • People living in poor housing conditions
  • Children < 6 years of age
  • Adults who work in industries known for lead exposure
  • Families of workers with occupational lead exposure 
  • People who live in areas with high lead contamination 
  • Pregnant women exposed to lead 

Your doctor may order this test if you show symptoms of lead toxicity. The symptoms and signs of lead toxicity include:

Children presenting with the following symptoms may also be screened for lead toxicity:

  • Hearing loss
  • Speech problems
  • Developmental delay
  • Learning difficulties
  • Sleep problems
  • Anaemia
  • Attention-deficit

You do not need any special preparation for this test. There is no need to fast either.

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Normal results:

A normal result indicates the absence of lead or the presence of only traces of lead in the blood. Traces of lead are reported as negative as they do not cause the harmful effects stated above. If the lead concentration in blood is less than 5 µg/dL (micrograms per decilitre), it may be considered normal for adults.

There is no safe blood lead concentration for children and pregnant women.

Abnormal results:

Lead levels >5 µg/dL in the blood are considered abnormal. 

The following are the cut-off values for lead exposure in children and adults:

  • Lead blood concentration between 5 and 10 µg/dL require follow-up. Individuals with blood lead levels of > 10 µg/dL are asked to evaluate their environment to locate and remove the possible sources of lead exposure.
  • Chelation treatment should be considered if lead blood levels are > 40 µg/dL in individuals who show symptoms of lead toxicity. Chelation therapy includes the administration of specific drugs that bind to the toxic metal and helps expel it through the urine.
  • Lead blood concentration of > 70 µg/dL is considered a medical emergency in adults whereas immediate treatment is recommended in children with lead levels of ≥ 45 µg/dL.

Disclaimer: All results must be clinically correlated with the patient’s complaints to make a complete and accurate diagnosis. The above information is provided from a purely educational point of view and is in no way a substitute for medical advice by a qualified doctor.

References

  1. Agency for Toxic Substances and Disease Registry [internet]. Center for Disease Control. Atlanta. GA. U.S. Toxicological Profile for Lead
  2. Center for Disease Control and Prevention [internet], Atlanta (GA): US Department of Health and Human Services; Childhood lead poisoning prevention
  3. American Academy of Pediatrics [internet]. Illinois (US). Detection of Lead Poisoning
  4. Center for Disease Control and Prevention [internet], Atlanta (GA): US Department of Health and Human Services; Educational Interventions for Children Affected by Lead
  5. Occupational Safety and Health Administration: United States Department of Labor [Internet]; Lead
  6. Center for Disease Control and Prevention [internet], Atlanta (GA): US Department of Health and Human Services; Adult Blood Lead Epidemiology and Surveillance (ABLES)
  7. Wilson D.D. McGraw-Hill’s Manual of Diagnostic and Laboratory Tests. Lead. 2008. Pg. 352- 353.
  8. American College of Obstetricians and Gynecologists. [internet], Bethesda (MD); Lead Screening During Pregnancy and Lactation
  9. Moreira MF, Neves EB. Use of urine lead level as an exposure indicator and its relationship to blood lead. Cad Saude Publica. 2008 Sep;24(9):2151-9. PMID: 18813691
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