What is a Fine Needle Aspiration Cytology (FNAC) test? 

Fine needle aspiration cytology or an FNAC is a diagnostic test that is used to check if a lump or a mass on the body is cancerous in nature. As the name suggests, this test is performed using a needle. A small amount of tissue, which needs to be analysed, is scraped and sent to a laboratory for analysis.

This procedure can be used to test for thyroid, salivary glands and lymph node illnesses. It is rapid and accurate and leaves no scars

  1. Why is an FNAC test performed?
  2. How do you prepare for an FNAC test?
  3. How is an FNAC test performed?
  4. What do FNAC test results indicate?

FNAC test is performed to determine the nature of superficial lumps- both palpable (can be felt on touch) and impalpable (can't be felt easily on touch), such as those on breast or neck.

It is specifically recommended when an abnormal lump is felt or detected during other diagnostic and routine medical procedures. Unlike its predecessors, FNAC test is non-invasive that is not associated with complications, such as scarring and pain

Also, the needle used in FNAC is extremely fine, with a hollow interior, compared to the regular needles used for drawing blood.

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No prior preparations are needed for performing this test. However, one can communicate clearly with the doctor as to what they can expect during the test.

Before the actual procedure is done, your doctor will ask you about the location of the lump and when did you first become aware of it. He/she will also inquire whether the lump feels painful or heavy. 

Next, he/she will check for the lump manually to understand its location or dimension. Thereafter, the actual procedure is performed. 

The skin where the test needs to be performed will first be sanitised with an antiseptic solution. If the lump is palpable, your doctor will press over the area gently to identify the spot through which the needle needs to be inserted. If, however, the lump cannot be felt, an ultrasound will be done to locate the area for needle insertion.

Once the lump is identified, your doctor will firmly hold it with one hand, and insert the needle with gentle pressure to withdraw the sample. 

Usually, 2-3 samples are required to make a diagnosis. Hence, the lump that needs to be tested is fixed between the fingers as the sample is drawn. 

The entire procedure (of inserting the needle and getting the sample) does not take more than 20-40 seconds. The needle will be taken out gently before blood is observed in it. The collected sample will be sent to a laboratory for analysis, and the results should be available in 3-4 days. 

This test has no complications when performed by an experienced and skilled practitioner. The only thing one might notice is slight bruising or short-lived tenderness in the area. 

Mild pain may be experienced while sample collection, though, the use of a local anaesthetic reduces the discomfort.

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The results could indicate the lump to be clearly benign (not cancerous), clearly malignant (cancerous) or nondefinitive (unclear and requires surgical biopsy for further study). 

Disclaimer: All results must be clinically correlated with the patient’s complaints to make a complete and accurate diagnosis. The above information is provided from a purely educational point of view and is in no way a substitute for medical advice by a qualified doctor.

References

  1. V Koo et.al. Fine needle aspiration cytology (FNAC) in the diagnosis of granulomatous lymphadenitis. Ulster Med J. 2006 Jan; 75(1): 59–64. PMID: 16457406
  2. Ahmad T. Fine needle aspiration cytology (FNAC) and neck swellings in the surgical outpatient. J Ayub Med Coll Abbottabad. 2008 Jul-Sep;20(3):30-2. PMID: 19610510
  3. Clinical Center. Ultra Sound Guided Fine Needle Aspiration Cytology (FNAC) of Liver and Pancreas Tumours. National Institutes of Health; U.S. Department of Health and Human Services [internet].
  4. J. Keith Killian et.al. Archival Fine-Needle Aspiration Cytopathology (FNAC) Samples. Journal of Molecular Diagnostics, Vol. 12, No. 6, November 2010
  5. MedlinePlus Medical Encyclopedia: US National Library of Medicine; Fine needle aspiration of the thyroid
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