What is a CDB (Cadmium Blood) test? 

Cadmium is a heavy metal that is often produced during the smelting of other metals such as zinc and lead. It can also be found in the batteries of mobile phones and other items such as fertilisers, paints, plastics, cigarettes.

Exposure to cadmium can cause flu-like symptoms and symptoms of the respiratory and gastrointestinal systems in the short term. Long-term exposure to this heavy metal can cause serious damage to the kidneys, lungs and bones. A cadmium blood test is mainly done to look for acute cadmium toxicity.  

Occupations which increase the risk of cadmium exposure include:

  • Battery manufacturing
  • Smelting of metals
  • Mining work
  • Textile work
  • Jewellery making
  • Stained glass window making
  • Solid waste recovery (municipality)
  • Jobs requiring welding and soldering
  • Manufacturing of cadmium alloys
  • Manufacturing of paints and plastics which contain cadmium

Soils treated with cadmium containing fertilisers and vegetables grown in contaminated soils are two other ways your body may be exposed to this heavy metal.

  1. Why is a Cadmium blood test performed?
  2. How do you prepare for a Cadmium blood test?
  3. How is a Cadmium blood test performed?
  4. Cadmium blood test results and normal range

A CDB test is mainly done to check for cadmium poisoning due to a recent exposure to this heavy metal.

Your doctor may suggest the CDB test if he/she notices the following symptoms associated with cadmium toxicity.

 Initial symptoms such as:

Late symptoms include:

Cadmium toxicity also affects the gastrointestinal system with symptoms such as:

A breastfeeding mother who has been exposed to cadmium may also pass it to her baby through the milk.

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You don't require any prior preparations before this test. However, your doctor is likely to ask you questions related to your health history and daily habits in order to find the probable cause for your symptoms. Inform the doctor if you are taking any medicines, such as supplements or prescription drugs. 

If you have been administered gadolinium- or iodine-containing contrast media, the specimen would be collected only after 96 hours (4 days) after the administration of contrast media as it can interfere with the test results.

In order to conduct the test, a blood sample is required.

The blood sample will be taken in the following way:

  • A health care provider will wrap an elastic band around your upper arm to restrict the flow of blood. This makes the veins present below the band to pop up so that a needle can be easily inserted
  • The injection site will be cleaned with alcohol and a needle will be inserted into the vein. Sometimes, more than one needle insertion may be required
  • Once enough blood has been collected, the band will be removed from your arm

It’s normal to feel lightheaded after the test. Some people also notice a bruise at the injection site, though all these symptoms fade away on their own. If the discomfort persists, inform your doctor as soon as possible. 

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Normal results:

The reference values for this test are 0.0-4.9 ng/mL (nanograms per millilitre). These values are applicable to all age groups. People who are occupationally exposed to cadmium would have a higher concentration of cadmium in their blood.

Still, normal blood cadmium levels should not exceed 5.0 ng/mL.

Abnormal results:

A result indicating higher than normal levels of cadmium is considered as abnormal. Acute toxicity is diagnosed if blood cadmium levels exceed 50 ng/mL.

Your doctor will conduct further tests in order to determine the damage that has been caused to the organs and to evaluate the severity of symptoms. Based on your results, your doctor will also provide a list of measures you can take to reduce and avoid further exposure to cadmium.

Disclaimer: All results must be clinically correlated with the patient’s complaints to make a complete and accurate diagnosis. The above information is provided from a purely educational point of view and is in no way a substitute for medical advice by a qualified doctor.

References

  1. National Pollutant Inventory. Department of the Environment and Energy. Australia. Cadmium and compounds
  2. Queensland Health. Government of Queensland, Australia; Environmental health
  3. Public Health England [internet]. Department of Health and Social Care. London. U.K. Cadmium, General information
  4. Agency for Toxic Substances and Disease Registry [internet]. Center for Disease Control. Atlanta. GA. U.S. Cadmium Toxicity Clinical Assessment - Laboratory Tests
  5. Moreau T, Lellouch J, Juguet B, et al. Blood cadmium levels in a general male population with special reference to smoking. Arch Environ Health.1983 May-Jun;38(3):163-7. PMID: 6870353
  6. Agency for Toxic Substances and Disease Registry [internet]. Center for Disease Control. Atlanta. GA. U.S. Cadmium Toxicity What Health Effects Are Associated With Acute High-Dose Cadmium Exposure?
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